Clinical Uncertainty Medicine: How Doctors Make Decisions When Evidence Is Incomplete, Risks Are Real, and Outcomes Are Unpredictable

This book examines one of the most demanding territories of contemporary medicine: clinical decision-making in contexts where certainty is incomplete, outcomes are unpredictable, and responsibility extends over time.Rather than offering protocols or prescriptive formulas, the work explores the ethical, conceptual, and practical foundations required to sustain care when clear answers are unavailable. It addresses persistent suffering, non-resolutive trajectories, multimorbidity, institutional pressures, technological mediation, and the limits of scientific knowledge as they appear in real clinical practice.The central concept developed throughout the book is clinical permanence — the professional capacity to remain responsible, present, and ethically grounded across prolonged and uncertain care processes. This perspective reframes longitudinal follow-up, therapeutic restraint, revision of decisions, and relational continuity as core competencies rather than secondary aspects of medicine.Drawing on interdisciplinary reflection, clinical reasoning theory, and ethical analysis, the text proposes that maturity in medical practice is not measured by the elimination of uncertainty, but by the way uncertainty is inhabited: with prudence, humility, transparency, and sustained commitment.The book is intended for physicians, healthcare professionals, educators, and researchers interested in clinical judgment, medical ethics, complex care, and the human dimensions of decision-making. Read more